Current Understanding of Lymphoproliferative Disorders.

Primary cutaneous T-cell and B-cell lymphomas may occur at any age and are defined by specific clinical, histopathologic, and immunophenotypic features. Clinical correlation is critical to differentiate indolent and aggressive entities, such as the lymphomatoid papulosis subtypes, which may have histopathologic and immunophenotypic features that are indistinguishable from aggressive cutaneous T cell lymphomas. Awareness of mycosis fungoides variants that overlap with benign conditions may help prevent misdiagnosis. Lymphoproliferative disorders do not require aggressive treatment or extensive staging. Watchful waiting is often appropriate.