Медицинская библиотека · Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025

Reactivation of cutaneous leishmaniasis in the context of non-HIV immunosuppression: a literature analysis.

de Souza Regina Maia, Tuon Felipe Francisco, Dantas Leticia Ramos, Imamura Rui, Funari Alexandre Pereira, Celeste Beatriz Julieta, Amato Valdir Sabbaga

СтатьяСистематический обзорПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

BACKGROUND

Immunosuppression increases the risk of primary cutaneous leishmaniasis (CL) infection and its reactivation. This systematic review examined CL reactivation in immunosuppressed patients, including those with autoimmune diseases and solid organ transplant recipients.

METHODS

A comprehensive literature search was conducted across multiple databases for studies published between May 1990 and May 2024.

RESULTS

Nine cases were selected, involving CL reactivation associated with immunosuppressive therapy for autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis, or following renal transplantation.

CONCLUSIONS

The management of CL during immunosuppressive therapy is challenging, necessitating different approaches for reactivation management.

Для цитирования: de Souza Regina Maia, Tuon Felipe Francisco, Dantas Leticia Ramos, Imamura Rui, Funari Alexandre Pereira, Celeste Beatriz Julieta, Amato Valdir Sabbaga. Reactivation of cutaneous leishmaniasis in the context of non-HIV immunosuppression: a literature analysis.. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2025. DOI: 10.1093/trstmh/traf038.

Предметные рубрики MeSH

Humans Leishmaniasis, Cutaneous Immunocompromised Host Immunosuppressive Agents Autoimmune Diseases Immunosuppression Therapy Male

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