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Войти в исследования Disability and rehabilitation · 2026
Home-based therapy for upper limb activity in children and adolescents with unilateral cerebral palsy: systematic review and meta-analysis.
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Lirio-Romero Cristina, Feys Hilde, López-Muñoz Purificación, Boyd Roslyn N, Coello-Villalón María, Romay-Barrero Helena, Basco-López Julián Ángel, Sgandurra Giuseppina, Beani Elena, Palomo-Carrión Rocío
Аннотация
PURPOSE: To analyze the effect of home-based therapy for upper limb activity in children and adolescents with unilateral cerebral palsy.
METHODS: PubMed, Cochrane Central Register of Controlled Trials, CINAHL, PsycINFO, and PEDro were systematically searched from inception to March 2026 for experimental studies addressing the effect of home-based therapies in participants aged from 2 to 18 years old. The DerSimonian and Laird method was used to compute pooled estimates of the standardized mean differences (SMD) and their respective 95% confidence intervals (CI). Subgroup analyses were performed based on the dosage of interventions.
RESULTS: Seventeen studies were included in this systematic review. Home-based therapies showed improvement in upper limb activity (SMD = 0.45; 95% CI: 0.30-0.60). No statistically significant differences were observed in relation to the intensity of intervention (hours per week). Meta-regression analysis revealed that none of the implementation-related moderators-including parental involvement, delivery format, dose profile, task relevance and contextual support-had a statistically significant effect on intervention outcomes (p > 0.05).
CONCLUSIONS: High-intensity home-based therapies have demonstrated promising findings in improving upper limb activity in children and adolescents with unilateral cerebral palsy. Further high-quality studies may assess the influence of intervention characteristics.
METHODS: PubMed, Cochrane Central Register of Controlled Trials, CINAHL, PsycINFO, and PEDro were systematically searched from inception to March 2026 for experimental studies addressing the effect of home-based therapies in participants aged from 2 to 18 years old. The DerSimonian and Laird method was used to compute pooled estimates of the standardized mean differences (SMD) and their respective 95% confidence intervals (CI). Subgroup analyses were performed based on the dosage of interventions.
RESULTS: Seventeen studies were included in this systematic review. Home-based therapies showed improvement in upper limb activity (SMD = 0.45; 95% CI: 0.30-0.60). No statistically significant differences were observed in relation to the intensity of intervention (hours per week). Meta-regression analysis revealed that none of the implementation-related moderators-including parental involvement, delivery format, dose profile, task relevance and contextual support-had a statistically significant effect on intervention outcomes (p > 0.05).
CONCLUSIONS: High-intensity home-based therapies have demonstrated promising findings in improving upper limb activity in children and adolescents with unilateral cerebral palsy. Further high-quality studies may assess the influence of intervention characteristics.