Neisseria meningitidis-associated chronic prostatitis following oral sexual exposure: a diagnostic challenge mimicking gonococcal urethritis.

Neisseria meningitidis is an uncommon cause of genitourinary infection, and chronic prostatitis caused by this organism has rarely been reported. A 34-year-old man presented with recurrent dysuria and urethral discharge after oral sexual exposure. Initially misdiagnosed as gonococcal urethritis, the patient achieved only partial improvement after empirical therapy. Culture of midstream urine and expressed prostatic secretions, confirmed by biochemical testing,MALDI-TOF MS and 16S rDNA sequencing, identified N. meningitidis. Targeted antimicrobial therapy resulted in clinical and microbiological resolution. This case highlights the importance of accurate pathogen identification in recurrent urethritis and prostatitis.