MedElevator
Войти в исследования Veterinary ophthalmology · 2025
Canine Herpesvirus-1 Ocular Infection in Japan: A Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Usami Kensuke, Komatsu Hiroyuki, Akasaka Minori, Morita Maresuke, Kumashiro Kayo, Inagaki Mao, Kobayashi Yoshitaka
Аннотация
OBJECTIVE: To describe the clinical manifestations and therapeutic outcomes of ocular infection caused by canine herpesvirus 1 (CHV-1), including both typical and atypical features.
ANIMAL STUDIED: A client-owned 5-year-old castrated male French Bulldog presented with dendritic corneal ulcers, quantitative tear deficiency, and corneal hypoesthesia in the left eye.
TREATMENT AND PROGRESSION: A diagnosis of CHV-1 ocular infection was made based on the characteristic presentation of dendritic corneal ulcers and confirmed by polymerase chain reaction (PCR) analysis of a conjunctival swab. Antiviral therapy with 0.1% idoxuridine ophthalmic solution was initiated on Day 8, and follow-up ophthalmic examinations were performed on Days 14, 37, and 58. To monitor viral shedding, conjunctival swabs were collected before and after the initiation of antiviral treatment and analyzed using the quantitative PCR method. Resolution of the corneal ulcers, along with improvement in corneal sensitivity and tear production, was observed. Quantitative PCR revealed a reduction in viral shedding following treatment. No recurrence of ocular lesions was noted by the time of the final follow-up examination.
CONCLUSION: To the authors' knowledge, this is the first documented case of CHV-1 ocular infection in an adult dog in Japan. These findings suggest that CHV-1 may cause not only characteristic corneal ulcers but also associated corneal hypoesthesia and quantitative tear deficiency.
ANIMAL STUDIED: A client-owned 5-year-old castrated male French Bulldog presented with dendritic corneal ulcers, quantitative tear deficiency, and corneal hypoesthesia in the left eye.
TREATMENT AND PROGRESSION: A diagnosis of CHV-1 ocular infection was made based on the characteristic presentation of dendritic corneal ulcers and confirmed by polymerase chain reaction (PCR) analysis of a conjunctival swab. Antiviral therapy with 0.1% idoxuridine ophthalmic solution was initiated on Day 8, and follow-up ophthalmic examinations were performed on Days 14, 37, and 58. To monitor viral shedding, conjunctival swabs were collected before and after the initiation of antiviral treatment and analyzed using the quantitative PCR method. Resolution of the corneal ulcers, along with improvement in corneal sensitivity and tear production, was observed. Quantitative PCR revealed a reduction in viral shedding following treatment. No recurrence of ocular lesions was noted by the time of the final follow-up examination.
CONCLUSION: To the authors' knowledge, this is the first documented case of CHV-1 ocular infection in an adult dog in Japan. These findings suggest that CHV-1 may cause not only characteristic corneal ulcers but also associated corneal hypoesthesia and quantitative tear deficiency.