Successful treatment of co-morbid schizophrenia and multiple sclerosis.

Multiple sclerosis (MS) has both neurological and psychiatric manifestations. Though depression, bipolar disorder and la belle indifference are commonly described, schizophrenia-like-psychosis is not widely reported with MS. Drug interactions and side effects make treatment, in such scenario, challenging. We, for the first time, report a patient with MS and paranoid schizophrenia successfully treated with concurrent use of clozapine and risperidone with interferon-beta-1a.