Journal of neurosurgery. Case lessons · 2025
Histiocytic sarcoma of the suprasellar region: illustrative case.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Natori Ikuya, Tanioka Daisuke, Kobayashi Yusuke, Shimizu Katsuyoshi, Mizutani Tohru, Omatsu Mutsuko, Nemoto Tetsuo
Аннотация
BACKGROUND: Histiocytic sarcoma (HS) is a rare malignant tumor of histiocytic origin, both morphologically and immunohistologically. Herein, the authors report the case of a suprasellar tumor confirmed as HS after craniotomy, which presented a diagnostic challenge.
OBSERVATIONS: A 58-year-old man presented with panhypopituitarism. To protect the patient's visual function and obtain a diagnosis, craniotomy was performed for tumor removal. Based on the immunohistological staining results, the tumor tested positive for both CD68 and CD163 and negative for CD1a, CD21, and MP0. Hence, the patient was diagnosed with HS. The tumor grew rapidly after surgery. Thus, the patient underwent reoperation. The patient's visual acuity and visual field deficits improved. However, he developed intractable electrolyte abnormalities caused by hypothalamic damage. Then, he exhibited intractable seizures and pneumonia and died 4 months after surgery.
LESSONS: This report emphasizes the rarity of suprasellar HS and its associated challenges in diagnosis and surgical treatment. https://thejns.org/doi/10.3171/CASE24297.
OBSERVATIONS: A 58-year-old man presented with panhypopituitarism. To protect the patient's visual function and obtain a diagnosis, craniotomy was performed for tumor removal. Based on the immunohistological staining results, the tumor tested positive for both CD68 and CD163 and negative for CD1a, CD21, and MP0. Hence, the patient was diagnosed with HS. The tumor grew rapidly after surgery. Thus, the patient underwent reoperation. The patient's visual acuity and visual field deficits improved. However, he developed intractable electrolyte abnormalities caused by hypothalamic damage. Then, he exhibited intractable seizures and pneumonia and died 4 months after surgery.
LESSONS: This report emphasizes the rarity of suprasellar HS and its associated challenges in diagnosis and surgical treatment. https://thejns.org/doi/10.3171/CASE24297.