Neurosurgery practice · 2023
Successful Treatment of Pure Aqueductal Pilomyxoid Astrocytoma and Arrested Hydrocephalus With Endoscopic Tumor Resection Followed by Chemotherapy: A Case Report and Technical Considerations.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Sakata Kiyohiko, Hashimoto Aya, Kotaki Yoshikuni, Yoshitake Hidenobu, Shimokawa Shoko, Komaki Satoru, Nakamura Hideo, Furuta Takuya, Morioka Motohiro
Аннотация
BACKGROUND AND IMPORTANCE: Pure aqueductal tumors are extremely rare and may lead to death, regardless of histopathology. We report the first case of pure aqueductal pilomyxoid astrocytoma in an adult woman with arrested hydrocephalus. Endoscopic tumor resection for securing aqueductal patency followed by chemotherapy allowed control of both the tumor and the hydrocephalus.
CLINICAL PRESENTATION: A 20-year-old woman presented with mild cognitive dysfunction and marked ventricular dilatation. She had no preoperative symptoms of intracranial hypertension, and her head circumference was more than 2 SDs above the 98th percentile. The aqueduct of Sylvius was entirely occupied by a neoplastic lesion with 2 periventricular nodules at the wall of the third ventricle and anterior horn of the right lateral ventricle. She was treated successfully with endoscopic tumor resection followed by chemotherapy, and the patency of the aqueduct of Sylvius was secured throughout the duration of treatment.
CONCLUSION: Pure aqueductal tumors may be an appropriate indication for endoscopic tumor resection to secure the aqueductal patency of cerebrospinal fluid. This case demonstrates the surgical technique of a combined rigid-flexible endoscopic transforaminal approach, which was a useful surgical intervention for the management of this patient.
CLINICAL PRESENTATION: A 20-year-old woman presented with mild cognitive dysfunction and marked ventricular dilatation. She had no preoperative symptoms of intracranial hypertension, and her head circumference was more than 2 SDs above the 98th percentile. The aqueduct of Sylvius was entirely occupied by a neoplastic lesion with 2 periventricular nodules at the wall of the third ventricle and anterior horn of the right lateral ventricle. She was treated successfully with endoscopic tumor resection followed by chemotherapy, and the patency of the aqueduct of Sylvius was secured throughout the duration of treatment.
CONCLUSION: Pure aqueductal tumors may be an appropriate indication for endoscopic tumor resection to secure the aqueductal patency of cerebrospinal fluid. This case demonstrates the surgical technique of a combined rigid-flexible endoscopic transforaminal approach, which was a useful surgical intervention for the management of this patient.