MedElevator
Войти в исследования Dermatology (Basel, Switzerland) · 2003
Clinical and therapeutic aspects of polymorphous light eruption.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Dummer Reinhard, Ivanova Katya, Scheidegger E Paul, Burg Günter
Аннотация
BACKGROUND: Polymorphous light eruption (PLE) is an idiopathic eruption induced by ultraviolet (UV) radiation (UVR).
OBJECTIVE: Evaluation of the clinical aspects, diagnostic criteria of PLE in a major Swiss referral center.
METHODS: 25 patients with PLE were tested with a standardized protocol for the assessment of photodermatoses.
RESULTS: 25 patients (22 women vs. 3 men) were identified. Papular and papular-vesicular eruptions were the most common clinical presentations. 6 of 25 patients had a reduced minimal erythema dose (MED) for UVA and 8 of 25 patients had a reduced MED for UVB. Photoprovocation was positive in 11 of 20 patients for UVA and 7 of 20 patients for UVB. Photohardening with narrow-band UVB was successful in 8 of 10 patients. Combined UVA/UVB therapy had a satisfactory effect in 10 of 15 patients. Narrow-band UVB therapy was still successful after ineffective UVA/UVB therapy.
CONCLUSION: The MED was of no value for the diagnosis of PLE. The typical lesions were reproduced by UVA and UVB photoprovocation. We recommend photohardening with narrow-band UVB (311 nm).
OBJECTIVE: Evaluation of the clinical aspects, diagnostic criteria of PLE in a major Swiss referral center.
METHODS: 25 patients with PLE were tested with a standardized protocol for the assessment of photodermatoses.
RESULTS: 25 patients (22 women vs. 3 men) were identified. Papular and papular-vesicular eruptions were the most common clinical presentations. 6 of 25 patients had a reduced minimal erythema dose (MED) for UVA and 8 of 25 patients had a reduced MED for UVB. Photoprovocation was positive in 11 of 20 patients for UVA and 7 of 20 patients for UVB. Photohardening with narrow-band UVB was successful in 8 of 10 patients. Combined UVA/UVB therapy had a satisfactory effect in 10 of 15 patients. Narrow-band UVB therapy was still successful after ineffective UVA/UVB therapy.
CONCLUSION: The MED was of no value for the diagnosis of PLE. The typical lesions were reproduced by UVA and UVB photoprovocation. We recommend photohardening with narrow-band UVB (311 nm).