Dermatology and therapy · 2026
Exploring the Potential Links between Telogen Effluvium, Alopecia Areata, Pressure-Induced Alopecia, and General Anesthesia: A Narrative Review.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Poniatowska Olga, Anand Łukasz Sein, Jakubczyk-Słabicka Anna, Płaza Dominik, Gammazza Antonella Marino, Barańska-Rybak Wioletta, Owczuk Radosław, Górska-Ponikowska Magdalena
Аннотация
BACKGROUND: Alopecia areata (AA), pressure-induced alopecia (PIA), and telogen effluvium (TE) are nonscarring forms of hair loss reported in patients undergoing surgical procedures under general anesthesia (GA). While AA is primarily autoimmune and stress-mediated, PIA arises from prolonged scalp pressure during surgery, and TE is typically triggered by metabolic or physiological stressors that induce a premature transition of anagen hairs into the telogen phase.
OBJECTIVE: This review aims to explore the emerging evidence linking GA to the onset or exacerbation of these alopecic types.
METHODS: Authors review currently available literature found in MEDLINE and Google Scholar databases and present it in a structured way.
RESULTS: Currently available literature supports the existence of a link between GA and AA, PIA, and TE, and proposes several potential mechanisms including immune dysregulation, ischemia, hypoxia, and systemic stress responses on the basis of current findings.
LIMITATIONS: Despite existing evidence, significant gaps remain in understanding the associations between various forms of alopecia and GA, owing to a lack of high quality, structured research.
CONCLUSIONS: There is a possible link between GA and various forms of alopecia, although further research to clarify the relationships, identify at-risk individuals, and inform perioperative hair loss management strategies is needed.
OBJECTIVE: This review aims to explore the emerging evidence linking GA to the onset or exacerbation of these alopecic types.
METHODS: Authors review currently available literature found in MEDLINE and Google Scholar databases and present it in a structured way.
RESULTS: Currently available literature supports the existence of a link between GA and AA, PIA, and TE, and proposes several potential mechanisms including immune dysregulation, ischemia, hypoxia, and systemic stress responses on the basis of current findings.
LIMITATIONS: Despite existing evidence, significant gaps remain in understanding the associations between various forms of alopecia and GA, owing to a lack of high quality, structured research.
CONCLUSIONS: There is a possible link between GA and various forms of alopecia, although further research to clarify the relationships, identify at-risk individuals, and inform perioperative hair loss management strategies is needed.