Frontiers in ophthalmology · 2026
A novel retrobulbar/intraconal surgical approach with combined cataract extraction and a modified AHMED ClearPath 250mm2 tube in the ciliary sulcus with an inferior sclerotomy in black and Afro-Latino patients with advanced glaucoma: a 6-month retrospective study.
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Laroche Daniel, Calderon Idaima, Nwokeji Imani
Аннотация
AIM: The purpose of this early safety and technical feasibility study was to evaluate the real-world performance of cataract extraction combined with a modified Ahmed ClearPath 250 mm² glaucoma drainage device placed in the retrobulbar/intraconal space with inferior sclerotomy in glaucoma patients, focusing on surgical tolerability, device stability, and preliminary safety outcomes while acknowledging limitations in sample size and follow-up that preclude definitive efficacy claims.
METHODS: This study was conducted at Advanced Eye Care of New York, a private practice located in NY, NY. This was a single-center, retrospective study of 12 patients who underwent combined phacoemulsification cataract surgery and glaucoma surgery using a retrobulbar/intraconal AHMED® ClearPath 250mm2 and an inferior sclerotomy technique. We report results at 6 months of follow-up. Investigated parameters were intraocular pressure, number of medications, mean deviation on visual field test, visual acuity, and adverse events.
RESULTS: Among all the 12 eyes undergoing combined cataract extraction and retrobulbar/intraconal AHMED® ClearPath 250mm² placement with inferior sclerotomy, mean IOP decreased from 18.08 to 14.83 mmHg (18.0% reduction) at 6 months. Topical medications decreased from 2.67 to 1.0 (62.5% reduction). Visual field MD remained stable (-18.59 dB to -18.15 dB). Five patients achieved trabeculectomy-like results (IOP ≤12 mmHg on ≤1 medication). Complications were limited to temporary post-op hypotony and shallow anterior chamber, with no bleb, diplopia, or additional astigmatism.
CONCLUSION: Cataract extraction combined with a modified Ahmed ClearPath 250 mm² glaucoma drainage device placed in the retrobulbar/intraconal space via inferior sclerotomy shows preliminary promise in reducing intraocular pressure and medication burden in Black and Afro-Latino patients with advanced glaucoma. These exploratory findings from a small cohort suggest technical feasibility and short-term safety, warranting further research with larger samples and longer follow-up to confirm efficacy and generalizability.
METHODS: This study was conducted at Advanced Eye Care of New York, a private practice located in NY, NY. This was a single-center, retrospective study of 12 patients who underwent combined phacoemulsification cataract surgery and glaucoma surgery using a retrobulbar/intraconal AHMED® ClearPath 250mm2 and an inferior sclerotomy technique. We report results at 6 months of follow-up. Investigated parameters were intraocular pressure, number of medications, mean deviation on visual field test, visual acuity, and adverse events.
RESULTS: Among all the 12 eyes undergoing combined cataract extraction and retrobulbar/intraconal AHMED® ClearPath 250mm² placement with inferior sclerotomy, mean IOP decreased from 18.08 to 14.83 mmHg (18.0% reduction) at 6 months. Topical medications decreased from 2.67 to 1.0 (62.5% reduction). Visual field MD remained stable (-18.59 dB to -18.15 dB). Five patients achieved trabeculectomy-like results (IOP ≤12 mmHg on ≤1 medication). Complications were limited to temporary post-op hypotony and shallow anterior chamber, with no bleb, diplopia, or additional astigmatism.
CONCLUSION: Cataract extraction combined with a modified Ahmed ClearPath 250 mm² glaucoma drainage device placed in the retrobulbar/intraconal space via inferior sclerotomy shows preliminary promise in reducing intraocular pressure and medication burden in Black and Afro-Latino patients with advanced glaucoma. These exploratory findings from a small cohort suggest technical feasibility and short-term safety, warranting further research with larger samples and longer follow-up to confirm efficacy and generalizability.