Hughes-Stovin Syndrome: A Rare Cause of Pulmonary Artery Aneurysm and Thrombosis-A Case Report.

Hughes-Stovin Syndrome (HSS) is a rare, life-threatening condition characterized by thrombophlebitis and pulmonary artery aneurysms, often viewed as a variant of Behçet's disease. Its diagnosis and management are challenging due to its rarity and overlapping symptoms with other vascular disorders. A 33-year-old male presented with massive hemoptysis and a history of recurrent oral and scrotal ulcers. Imaging revealed bilateral pulmonary emboli, a pulmonary artery aneurysm, and a large right atrial thrombus. These findings, coupled with his clinical history, led to a diagnosis of HSS. A multidisciplinary team initiated anticoagulation for the thrombus and immunosuppressive therapy (steroids, cyclophosphamide). Follow-up imaging showed improvement in both the aneurysm and thrombus. This case highlights the complexity of diagnosing and managing HSS. Early recognition, supported by a collaborative approach, is critical to improving outcomes in this rare syndrome.