Journal of cataract and refractive surgery · 2026
Rate of posterior capsular opacification and complications of YAG capsulotomy in patients with uveitis.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Ng Hannah W, Al-Ani Haya H, Mpe Dineo, Sims Joanne L, Niederer Rachael L
Аннотация
PURPOSE: To determine the rate of posterior capsular opacification (PCO) and outcomes and complications of YAG capsulotomy after cataract surgery in eyes with uveitis.
SETTING: Tertiary public hospital setting in Auckland, New Zealand, between 2009 and 2023.
DESIGN: Retrospective observational cohort study.
METHODS: Patients who underwent cataract surgery after a diagnosis of uveitis were included. The main outcome measures studied were time from cataract surgery to development of PCO and flare of uveitis after YAG capsulotomy.
RESULTS: In 4430 patients with uveitis, cataract surgery was performed in 596 patients (13.5%, 746 eyes). PCO developed in 250 eyes with a median time to PCO of 77 months. PCO developed in 17.3% (95% CI 14.6%-20.5%) by 1 year, 24.2% (95% CI 21.0%-27.8%) by 2 years, and 33.8% (95% CI 30.3%-37.7%) by 5 years. 120 eyes underwent YAG capsulotomy during the study period. Complications occurred in 19 participants (15.8%) and included uveitis flare (15.0%), cystoid macular edema (3.3%), and retinal detachment (0.8%). On multivariate analysis, younger age was associated with higher risk of uveitis flare (odds ratio [OR] 0.968, P = .038) and 3 months quiescence with lower risk of flare (OR 0.190, P = .004).
CONCLUSIONS: PCO is a common complication after cataract surgery in participants with uveitis, occurring in more than one-third of patients by 5 years. Complications of YAG capsulotomy occur in 15.8% with increased frequency in younger participants and in those with <3 months of uveitis quiescence.
SETTING: Tertiary public hospital setting in Auckland, New Zealand, between 2009 and 2023.
DESIGN: Retrospective observational cohort study.
METHODS: Patients who underwent cataract surgery after a diagnosis of uveitis were included. The main outcome measures studied were time from cataract surgery to development of PCO and flare of uveitis after YAG capsulotomy.
RESULTS: In 4430 patients with uveitis, cataract surgery was performed in 596 patients (13.5%, 746 eyes). PCO developed in 250 eyes with a median time to PCO of 77 months. PCO developed in 17.3% (95% CI 14.6%-20.5%) by 1 year, 24.2% (95% CI 21.0%-27.8%) by 2 years, and 33.8% (95% CI 30.3%-37.7%) by 5 years. 120 eyes underwent YAG capsulotomy during the study period. Complications occurred in 19 participants (15.8%) and included uveitis flare (15.0%), cystoid macular edema (3.3%), and retinal detachment (0.8%). On multivariate analysis, younger age was associated with higher risk of uveitis flare (odds ratio [OR] 0.968, P = .038) and 3 months quiescence with lower risk of flare (OR 0.190, P = .004).
CONCLUSIONS: PCO is a common complication after cataract surgery in participants with uveitis, occurring in more than one-third of patients by 5 years. Complications of YAG capsulotomy occur in 15.8% with increased frequency in younger participants and in those with <3 months of uveitis quiescence.