Archives of medical research · 2000
Paradoxic response to diazepam in complex partial status epilepticus.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Al Tahan A
Аннотация
BACKGROUND: Antiepileptics including benzodiazepines have long been recognized to provoke seizures and precipitate status epilepticus occasionally. This has a special clinical importance in the case of diazepam because of its use as first choice medication in its management. This report is intended to highlight the clinical importance of such a situation.
METHODS: The clinical course of a 28-year old man with complex partial status, which lasted for two months, is described in detail.
RESULTS: Paradoxic response to diazepam was documented under EEG monitoring. A similar response was also noted for midazolam, and had probably contributed in exacerbating and prolonging the duration of status.
CONCLUSION: Paradoxic response to diazepam and midazolam is rare, but may be under-recognized. It should be considered in the setting of refractory status epilepticus.
METHODS: The clinical course of a 28-year old man with complex partial status, which lasted for two months, is described in detail.
RESULTS: Paradoxic response to diazepam was documented under EEG monitoring. A similar response was also noted for midazolam, and had probably contributed in exacerbating and prolonging the duration of status.
CONCLUSION: Paradoxic response to diazepam and midazolam is rare, but may be under-recognized. It should be considered in the setting of refractory status epilepticus.