Medicine · 2026
Subungual melanoma of the fifth digit: A case report of a rare cutaneous malignancy documented in Syria.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Haj Osman Osama, Alsayed Yhia, Abo Saada Sawsan, Alkhamis Ahmad, Hintaieh Nour, Ghabreau Lina, Etr Aladdin
Аннотация
RATIONALE: Subungual melanoma is the rarest subtype of cutaneous melanoma, accounting for approximately 1.9% of cases. Involvement of the fifth digit is exceptionally uncommon, often contributing to delayed diagnosis and poor outcomes.
PATIENT CONCERNS: We report a case involving a 45-year-old male patient who presented with longitudinal melanonychia, a positive Hutchinson's sign, and ulceration of the nail plate on the right fifth finger.
DIAGNOSES: Histopathological analysis confirmed subungual melanoma with a Breslow thickness of 4.3 mm.
INTERVENTIONS: The patient underwent surgical amputation at the proximal interphalangeal joint, accompanied by a sentinel lymph node biopsy. The excised specimen demonstrated clear margins, and the sentinel lymph node biopsy was negative. Contrast-enhanced computed tomography of the chest, abdomen, and pelvis revealed no evidence of metastatic disease.
OUTCOMES: At 2-month follow-up, the patient reported good wound healing and no evidence of recurrence, though he was subsequently lost to follow-up. This case highlights the diagnostic challenges of subungual melanoma, particularly in the fifth digit, and underscores the importance of maintaining a high index of suspicion for pigmented nail lesions.
LESSONS: Early biopsy and timely surgical management remain critical for improving prognostic outcomes in rare presentations of melanoma.
PATIENT CONCERNS: We report a case involving a 45-year-old male patient who presented with longitudinal melanonychia, a positive Hutchinson's sign, and ulceration of the nail plate on the right fifth finger.
DIAGNOSES: Histopathological analysis confirmed subungual melanoma with a Breslow thickness of 4.3 mm.
INTERVENTIONS: The patient underwent surgical amputation at the proximal interphalangeal joint, accompanied by a sentinel lymph node biopsy. The excised specimen demonstrated clear margins, and the sentinel lymph node biopsy was negative. Contrast-enhanced computed tomography of the chest, abdomen, and pelvis revealed no evidence of metastatic disease.
OUTCOMES: At 2-month follow-up, the patient reported good wound healing and no evidence of recurrence, though he was subsequently lost to follow-up. This case highlights the diagnostic challenges of subungual melanoma, particularly in the fifth digit, and underscores the importance of maintaining a high index of suspicion for pigmented nail lesions.
LESSONS: Early biopsy and timely surgical management remain critical for improving prognostic outcomes in rare presentations of melanoma.