Eradication of Salmonella enteritidis periprosthetic hip infection using a custom-made articulating spacer: A case report.

Periprosthetic joint infection (PJI) remains a challenging complication following total hip arthroplasty (THA), commonly managed through a two-stage revision which can lead to significant morbidity. In this article, we present a rare case of Salmonella enteritidis PJI, initially presenting as prosthetic hip dislocation. Preoperative hip aspiration utilizing blood culture bottles enabled early identification of the organism and guided targeted antimicrobial therapy. The patient underwent revision THA using a well-fixed custom-made articulating spacer (CUMARS) construct, with targeted antibiotic-loaded bone cement. One-year follow-up demonstrated successful eradication of the infection, stable implant fixation, and good functional outcomes. In conclusion, this case underscores the importance of diagnostic hip aspiration and highlights the potential of the CUMARS technique as an effective and durable solution for managing rare PJIs caused by atypical organisms such as Salmonella enteritidis.