Hematology (Amsterdam, Netherlands) · 2025
Budd-chiari syndrome associated with acute promyelocytic leukemia: a case and literature review.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Wang Honglei, Guan Jing, Zeng Jia, Wang Ting, Lang Xu, Fu Rong
Аннотация
BACKGROUND: Acute promyelocytic leukemia (APL) is prone to hemorrhage and thrombosis during onset and induction treatment. Occasionally, severe and rare thrombosis can occur, which deserves our attention. Such as Budd-Chiari syndrome (BCS). BCS is a rare and severe disease caused by occlusion of the hepatic veins. Ascites, abdominal pain, and abnormal liver function are the first manifestations of this disease.
CASE PRESENTATION: We report the case of a high-risk patient with APL with acute liver failure and massive ascites during induction therapy due to BCS. He was in a critical condition between life-threatening bleeding tendency and thrombosis. The patient was successfully treated with thrombectomy of the right hepatic vein and balloon dilatation therapy, which provided time for APL treatment.
CONCLUSION: Our case highlights an uncommon venous thrombosis due to APL. We hope to provide some new treatment options for clinicians.
CASE PRESENTATION: We report the case of a high-risk patient with APL with acute liver failure and massive ascites during induction therapy due to BCS. He was in a critical condition between life-threatening bleeding tendency and thrombosis. The patient was successfully treated with thrombectomy of the right hepatic vein and balloon dilatation therapy, which provided time for APL treatment.
CONCLUSION: Our case highlights an uncommon venous thrombosis due to APL. We hope to provide some new treatment options for clinicians.