Autonomic neuroscience : basic & clinical · 2026
Exploring the association between interoceptive awareness and neuropsychiatric symptoms in people living with Parkinson's disease.
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Medina-Pérez María Fernanda, Hernández-Medrano Ana Jimena, Rivera-Monroy Germán, Cervantes-Arriaga Amin, Rodríguez-Violante Mayela, Solís-Vivanco Rodolfo
Аннотация
Interoceptive awareness (IA) supports emotional processing and may be affected in people with Parkinson's disease (PwP), where depression and anxiety are common. We examined associations between IA, neuropsychiatric symptoms, cognition, and disease severity in PwP. In a case-control study, 50 PwP and 25 controls completed the MAIA, HDRS, HARS, MoCA, and MDS-UPDRS. IA did not differ between groups. In PwP, lower MAIA Not-Worrying and Self-Regulation scores correlated with depression, anxiety, and disease severity. In addition, lower MAIA Self-Regulation scores correlated with higher orthostatic hypotension symptoms. Reduced interoceptive confidence in PwP is associated with neuropsychiatric burden and perceived autonomic symptom burden.