Internal medicine (Tokyo, Japan) · 2025
Coexistence of Relapsing Polychondritis, Crohn's Disease, and Pyoderma Gangrenosum Treated Successfully with Adalimumab: A Case Report and Literature Review.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Yamazaki Shun, Tominaga Kentaro, Watanabe Kotaro, Watanabe Makoto, Kondo Shuhei, Sakai Norihiro, Yoshida Tomoaki, Kojima Yuichi, Watanabe Yusuke, Kawata Yuzo, Kimura Naruhiro, Takahashi Kazuya, Sato Hiroki, Ikarashi Satoshi, Kamimura Hiroteru, Hayashi Kazunao, Terai Shuji
Аннотация
Relapsing polychondritis (RP) is a rare, progressive, immune-mediated systemic inflammatory disease of unknown etiology characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with autoimmune disease. However, co-occurrence of RP and Crohn's disease (CD) has rarely been reported. We herein report a case of coexisting RP, CD, and pyoderma gangrenosum that was successfully treated with adalimumab in combination with methotrexate. We believe that this case and literature review will facilitate the accurate and prompt diagnosis and treatment of RP combined with CD and various other complications.