Unique Pathological Findings of Polarized Calcium Oxalate Crystals in Spondylodiscitis of an ESRD Hemodialysis Patient: A Case Report.

Patients with end-stage renal disease (ESRD) undergoing chronic hemodialysis are at an increased risk of developing spondylodiscitis, an infectious condition affecting the vertebral column. In this case report, we present a 22-year-old male with ESRD, a history of hyperoxaluria, nephrolithiasis, and anemia, who developed spondylodiscitis. Notably, pathological examination of tissue samples obtained during surgical intervention revealed the presence of polarized calcium oxalate crystals within the lumbar laminae and spinal discs, a rare finding in this clinical context. The deposition of these crystals may have contributed to the development and progression of spondylodiscitis by creating an environment conducive to bacterial growth and infection. This case highlights the importance of comprehensive pathological assessment in ESRD patients with spondylodiscitis, as it may uncover uncommon manifestations that could have implications for disease management. Further research is necessary to elucidate the underlying mechanisms of this rare presentation and its impact on the clinical course and treatment of spondylodiscitis in ESRD patients undergoing hemodialysis.