Herpes simplex virus in chronic relapsing keratoconjunctivitis.

In a patient with a 5-month history of chronic relapsing keratoconjunctivitis, herpes simplex virus antigen was disclosed by immunofluorescence test in material obtained by conjunctival scraping, and the symptoms resolved following acyclovir (Zovirax) treatment. The diagnostic difficulties with patients presenting without symptoms suggestive of herpes simplex virus may be responsible for the lack of similar reports.