Psychological Impact of Biologic Therapy in CRSwNP: A Pilot Study.

Biologic therapies not only improve the inflammatory profile of chronic rhinosinusitis with nasal polyps (CRSwNP) but also appear to enhance patients' psychological well-being. Depression, anxiety, and stress levels significantly decrease after treatment with Dupilumab or Mepolizumab, suggesting a possible link between disease control and psychological improvement. This pilot study supports the integration of psychological assessment into the management of chronic airway diseases.