Central Diabetes Insipidus and Brain Herniation Secondary to Cryptococcal Meningitis in a Dog.

Central diabetes insipidus (CDI) should be considered in neurologic patients with persistent polyuria and rising sodium concentrations despite appropriate fluid therapy. Earlier recognition, serial urine concentration monitoring, and desmopressin administration may help prevent severe hypernatremia, although outcomes may remain poor in patients with progressive intracranial disease.