JACC. Case reports · 2026
Cardiac Paraganglioma.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Shereef Hammam, Bhatia Atul
Аннотация
BACKGROUND: Cardiac paragangliomas are rare neuroendocrine tumors that can present with catecholaminergic symptoms or be discovered incidentally. Multimodality imaging and genetic testing are central to diagnosis and management.
CASE SUMMARY: A 76-year-old woman with paroxysmal atrial fibrillation and recurrent gastrointestinal bleeding underwent preprocedural imaging with cardiac computed tomography angiography for left atrial appendage occlusion, which revealed a large mass near the ascending aorta encasing the proximal right coronary artery. Surgical resection of the mass was performed. Histopathology confirmed the presence of paraganglioma. Genetic analysis identified a hereditary gene mutation.
DISCUSSION: Cardiac paragangliomas are rare tumors that require a high index of suspicion. This case demonstrates the diagnostic value of advanced imaging in cardiac tumors and illustrates the role of genetic testing in identifying heritable paraganglioma syndromes.
TAKE-HOME MESSAGES: Multimodality imaging is important in the diagnosis of cardiac masses. Surgical resection is the primary treatment for cardiac paragangliomas.
CASE SUMMARY: A 76-year-old woman with paroxysmal atrial fibrillation and recurrent gastrointestinal bleeding underwent preprocedural imaging with cardiac computed tomography angiography for left atrial appendage occlusion, which revealed a large mass near the ascending aorta encasing the proximal right coronary artery. Surgical resection of the mass was performed. Histopathology confirmed the presence of paraganglioma. Genetic analysis identified a hereditary gene mutation.
DISCUSSION: Cardiac paragangliomas are rare tumors that require a high index of suspicion. This case demonstrates the diagnostic value of advanced imaging in cardiac tumors and illustrates the role of genetic testing in identifying heritable paraganglioma syndromes.
TAKE-HOME MESSAGES: Multimodality imaging is important in the diagnosis of cardiac masses. Surgical resection is the primary treatment for cardiac paragangliomas.