BMJ open · 2025
Epidemiology and disease burden of connective tissue disease-associated interstitial lung disease (CTD-ILD) in Asia: a systematic review and meta-analysis protocol.
СтатьяНазвание и аннотация: Перевод в очереди
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Chua Felix, Subramaniam Sivasangari, Lai Wei Hong, Tan Shirin Hui, Yean Hazel Ru Ann, Kho Sze Shyang, Yew Jasmine Sze Yin, Hong Hooi Chuen, Ng Cheryl Chun Man, Sirol Aflah Syazatul Syakirin, Mohd Zaidi Norshahiratul Atiqah, Ong Voon H, Chai Gin Tsen, Ang Swee Hung, Maamor Hasnah, Muhamad Nor Asiah
Аннотация
INTRODUCTION: Interstitial lung diseases (ILD) associated with an underlying connective tissue disease (CTD), also known as a systemic autoimmune rheumatic disease or SARD, are chronic conditions with a tendency to progress. CTD-ILDs are increasingly diagnosed and pose an important global health challenge. This systematic review aims to provide an overarching evaluation of their epidemiology and disease burden in Asia. In this review, the term CTD-ILD will be used to denote all major forms of ILD arising in the context of a SARD.
METHODS AND ANALYSIS: This systematic review will adhere to the standards of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, including a flow diagram to depict the process by four independent reviewers that will assess titles and abstracts against the following predetermined criteria. A systematic review of the literature search published from 2000 to 2024 will be conducted using five electronic databases including PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library and Web of Science. Publications that meet the inclusion criteria of this review will be subjected to a full-text review to extract relevant data. Collated data will be analysed and organised into categories based on the expected outcome and objectives. The quality of published evidence, including heterogeneity across studies, will be checked against PRISMA checklists and assessed by Newcastle-Ottawa Scale.
ETHICS AND DISSEMINATION: Ethics approval is not applicable for this study since no original data will be collected. The findings of this review will be disseminated through a peer-reviewed publication in a scientific journal and conference communications, with the aim of contributing insights to the field by identifying research gaps and informing clinical practice.
PROSPERO REGISTRATION NUMBER: The protocol of this systematic review is registered with the National Medical & Research Register (ID-24-03600-GUB) and International Prospective Register of Systematic Reviews PROSPERO (CRD420251037095).
METHODS AND ANALYSIS: This systematic review will adhere to the standards of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, including a flow diagram to depict the process by four independent reviewers that will assess titles and abstracts against the following predetermined criteria. A systematic review of the literature search published from 2000 to 2024 will be conducted using five electronic databases including PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library and Web of Science. Publications that meet the inclusion criteria of this review will be subjected to a full-text review to extract relevant data. Collated data will be analysed and organised into categories based on the expected outcome and objectives. The quality of published evidence, including heterogeneity across studies, will be checked against PRISMA checklists and assessed by Newcastle-Ottawa Scale.
ETHICS AND DISSEMINATION: Ethics approval is not applicable for this study since no original data will be collected. The findings of this review will be disseminated through a peer-reviewed publication in a scientific journal and conference communications, with the aim of contributing insights to the field by identifying research gaps and informing clinical practice.
PROSPERO REGISTRATION NUMBER: The protocol of this systematic review is registered with the National Medical & Research Register (ID-24-03600-GUB) and International Prospective Register of Systematic Reviews PROSPERO (CRD420251037095).