Orbit (Amsterdam, Netherlands) · 2026
Health-related quality of life after orbital exenteration for COVID-19-associated rhino-orbital-cerebral mucormycosis in South India: a cross-sectional SF-36 study and systematic review.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Dsouza Ashel Chelsea, Kaur Jasleen, M Swathi, Shoyaib Khazi K Md, Dsouza Aster Chelson, Sathyanarayan Anudeep, J T Chinmayee
Аннотация
PURPOSE: Rhino-orbital-cerebral mucormycosis (ROCM) surged during the COVID-19 pandemic, often necessitating orbital exenteration for disease control. While survival outcomes are increasingly reported, long-term health-related quality of life (HRQoL) among survivors remains poorly characterized, particularly in low- and middle-income settings. This study evaluated HRQoL using the SF-36 among survivors of COVID-19-associated ROCM who underwent orbital exenteration.
METHODS: In this cross-sectional study, adult survivors of orbital exenteration for COVID-19-associated ROCM treated at a tertiary center in South India completed the SF-36 questionnaire. SF-36 domain and component scores were compared with Indian normative values using Welch's t-tests. Multivariable linear regression assessed associations between demographic and clinical factors and Physical (PCS) and Mental (MCS) Component Summary scores. A parallel narrative review of QoL studies in COVID-19-associated mucormycosis was conducted.
RESULTS: Thirty-five survivors (mean age 47.0 ± 13.5 years; 60% female) were included. PCS scores were comparable to Indian norms (50.20 vs 47.87; p = 0.116), whereas MCS scores were significantly lower (36.30 vs 51.63; p < 0.001). Social Functioning showed the greatest deficit (-38.28 points vs norms). Male sex was associated with higher PCS, and receipt of any COVID-19 vaccination was associated with higher MCS.
CONCLUSIONS: Survivors of orbital exenteration for COVID-19-associated ROCM exhibit preserved physical health but substantial impairments in mental health and social functioning, highlighting the need for integrated psychosocial care and accessible rehabilitation in post-ROCM survivorship.
METHODS: In this cross-sectional study, adult survivors of orbital exenteration for COVID-19-associated ROCM treated at a tertiary center in South India completed the SF-36 questionnaire. SF-36 domain and component scores were compared with Indian normative values using Welch's t-tests. Multivariable linear regression assessed associations between demographic and clinical factors and Physical (PCS) and Mental (MCS) Component Summary scores. A parallel narrative review of QoL studies in COVID-19-associated mucormycosis was conducted.
RESULTS: Thirty-five survivors (mean age 47.0 ± 13.5 years; 60% female) were included. PCS scores were comparable to Indian norms (50.20 vs 47.87; p = 0.116), whereas MCS scores were significantly lower (36.30 vs 51.63; p < 0.001). Social Functioning showed the greatest deficit (-38.28 points vs norms). Male sex was associated with higher PCS, and receipt of any COVID-19 vaccination was associated with higher MCS.
CONCLUSIONS: Survivors of orbital exenteration for COVID-19-associated ROCM exhibit preserved physical health but substantial impairments in mental health and social functioning, highlighting the need for integrated psychosocial care and accessible rehabilitation in post-ROCM survivorship.