Diagnosis of Mycoplasma Pneumoniae-Induced Rash and Mucositis in a Saudi Female Patient: A Case Report.

Mycoplasma-induced rash and mucositis (MIRM), a new distinct entity, demonstrates a unique presentation in contrast to other mucocutaneous eruptions. Its clinical features include prominent mucositis, limited body surface area involvement, and confirmation of infection with Mycoplasma pneumoniae. Despite its infrequency, MIRM demands prompt recognition and management due to its significant morbidity and mortality. A 13-year-old female had been reported with a high fever, mild productive cough, bilateral eyelid swelling, severe conjunctival erythema, eye discharge, a rash on her palms and soles, and mouth mucositis caused by Mycoplasma pneumoniae. Despite initial antibiotic treatment, the patient was not improving, necessitating the administration of intravenous methylprednisolone, which resulted in significant clinical improvement. This case report indicates the significance of investigating Mycoplasma pneumoniae as a possible etiology in patients with blistering skin and mucosal involvement, even in the absence of respiratory symptoms. It also highlights the diagnostic dilemma and significant ocular morbidity associated with MIRM, which necessitated ophthalmological management.