[Cryoglobulinemia, hemorrhagic vasculitis skin changes in hepatopathy].

Cryoglobulins in the blood of patients with liver diseases may be associated with immunologically induced cutaneous vasculitis and haemorrhage. A personal case of chronic cirrhogenic liver disease with progression to liver insufficiency is presented. The picture included IgG, IgA and IgM cryoglobulinaemia and palpable purpura. The main features of primary and secondary or symptomatic cryoglobulinaemia are described, and an account is given of the mostly recent literature on the association between cryoglobulinaemia and liver diseases. Its pathogenesis and possible forms of treatment are also discussed.