General thoracic and cardiovascular surgery · 2025
Blood loss and prolonged air leak reduction by applying TenaTac® gelatine patch after major pulmonary minimal-invasive resection.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rivera Caroline, Perrot Cyril, Mazeres Florence, Rive Elodie
Аннотация
OBJECTIVE: Reduction of bleeding and prolonged air leak (>5 days) following major lung resection remains a challenge. Hemostasis and aerostasis devices can facilitate earlier pleural de-drainage and fast-track. Our objectives were to evaluate the efficacy of TenaTac® (an elastic, adhering patch approved as a medical device) in reducing bleeding and prolonged air leak after major lung resection.
METHODS: This monocentric retrospective case-control study, using prospectively collected data, includes 60 patients who underwent, between 2022 and 2024, minimally invasive robot-assisted lobectomy or segmentectomy: 30 with TenaTac® vs. 30 with other devices. Data were extracted from Epithor, the French national database, with ethics committee validation.
RESULTS: Patients characteristics, Index of Prolonged Air Leak, and surgical procedures were similar in both groups (NS). TenaTac® hemostatic benefit was comparable to other devices (p = 0.56). Prolonged air leak rate was significantly lower with TenaTac® (3%) than for control devices (37%) (p = 0.0004). Post-operative air leakage duration was significantly shorter in TenaTac® group than in control group (2.23 ± 2.57 vs. 4.23 ± 3.87 days, p = 0.01). Mean drainage duration and length of stay were both reduced with TenaTac® by 36 hours. No significant difference was observed between the two groups in terms of morbidity (90-day post-operative complications classified as Clavien-Dindo grade>II, p = 0.33), readmission rates (nil), or 90-day mortality (no deaths).
CONCLUSIONS: Numerous hemostatic or aerostatic devices have been previously evaluated without achieving consensus in the prevention of prolonged air leak. As an absorbable, adherent gelatine patch, TenaTac® significantly reduces the incidence of prolonged air leak after major lung resection.
METHODS: This monocentric retrospective case-control study, using prospectively collected data, includes 60 patients who underwent, between 2022 and 2024, minimally invasive robot-assisted lobectomy or segmentectomy: 30 with TenaTac® vs. 30 with other devices. Data were extracted from Epithor, the French national database, with ethics committee validation.
RESULTS: Patients characteristics, Index of Prolonged Air Leak, and surgical procedures were similar in both groups (NS). TenaTac® hemostatic benefit was comparable to other devices (p = 0.56). Prolonged air leak rate was significantly lower with TenaTac® (3%) than for control devices (37%) (p = 0.0004). Post-operative air leakage duration was significantly shorter in TenaTac® group than in control group (2.23 ± 2.57 vs. 4.23 ± 3.87 days, p = 0.01). Mean drainage duration and length of stay were both reduced with TenaTac® by 36 hours. No significant difference was observed between the two groups in terms of morbidity (90-day post-operative complications classified as Clavien-Dindo grade>II, p = 0.33), readmission rates (nil), or 90-day mortality (no deaths).
CONCLUSIONS: Numerous hemostatic or aerostatic devices have been previously evaluated without achieving consensus in the prevention of prolonged air leak. As an absorbable, adherent gelatine patch, TenaTac® significantly reduces the incidence of prolonged air leak after major lung resection.