Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
Modifiable Risk Factors for Symptom Burden in Chronic Rhinosinusitis With Nasal Polyps: The Role of Obesity and Sleep Apnoea.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
García-Fernández Javier Modesto, Sánchez-Torices María Soledad, Gómez-Gallego María Pilar, Feliz-Fernández Miguel Ángel, Montilla-Ibáñez María Alharilla, Lomas-Vega Rafael
Аннотация
OBJECTIVE: To identify sociodemographic and clinical predictors of symptom severity and quality of life (QoL) impairment in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), diagnosed according to the latest EPOS 2020 criteria.
STUDY DESIGN: Cross-sectional analytical study.
SETTING: Tertiary Care Center (University Hospital of Jaén, Spain).
METHODS: A total of 188 patients diagnosed with CRSwNP were evaluated. Symptom severity and QoL were assessed using the Nasal Obstruction Symptom Evaluation (NOSE-E) and the Sino-Nasal Outcome Test (SNOT-22). Multiple linear regression analysis was used to identify predictors of symptom burden.
RESULTS: Higher body mass index (BMI) and the presence of sleep apnoea were independently associated with increased symptom severity, as measured by both the NOSE-E (adj. R 2 = 0.224, p = 0.002) and the SNOT-22 (adj. R 2 = 0.242, p = 0.005). Smoking was associated in the bivariate analysis but was not retained in the multivariate models.
CONCLUSION: BMI and sleep apnoea are independent predictors of greater symptom burden and poorer QoL in CRSwNP. These findings highlight the importance of incorporating weight management and sleep apnoea screening into the multidisciplinary management of CRSwNP to improve patient outcomes.
STUDY DESIGN: Cross-sectional analytical study.
SETTING: Tertiary Care Center (University Hospital of Jaén, Spain).
METHODS: A total of 188 patients diagnosed with CRSwNP were evaluated. Symptom severity and QoL were assessed using the Nasal Obstruction Symptom Evaluation (NOSE-E) and the Sino-Nasal Outcome Test (SNOT-22). Multiple linear regression analysis was used to identify predictors of symptom burden.
RESULTS: Higher body mass index (BMI) and the presence of sleep apnoea were independently associated with increased symptom severity, as measured by both the NOSE-E (adj. R 2 = 0.224, p = 0.002) and the SNOT-22 (adj. R 2 = 0.242, p = 0.005). Smoking was associated in the bivariate analysis but was not retained in the multivariate models.
CONCLUSION: BMI and sleep apnoea are independent predictors of greater symptom burden and poorer QoL in CRSwNP. These findings highlight the importance of incorporating weight management and sleep apnoea screening into the multidisciplinary management of CRSwNP to improve patient outcomes.