Henoch-Schönlein purpura in an adult patient: extragastric, cutaneous manifestation of helicobacter pylori infection.

Today there is evidence that Helicobacter pylori has a critical role in different extragastric diseases. The discovery of a number of other new Helicobacter species has stimulated research into different extragastric diseases, in which an infectious hypothesis is plausible. Enterohepatic Helicobacter species have been hypothesized to play a role in different disorders including the extragastric manifestations of H. pylori infection. The authors present a case of Henoch-Schönlein purpura in an adult patient with Helicobacter pylori infection and disease regression after triple anti-Helicobacter eradication therapy. The patient was monitored, over a follow-up period of almost 9 years after eradication of Helicobacter pylori presence, by clinical examination as well as serological findings. There was no disease reccurence during the follow-up period and no markers of Helicobacter pylori reinfection. Since disease recurrence occurs throughout weeks to months, the authors conclude that Henoch-Schonlein purpura is a possible extragastric, cutaneous manifestation of Helicobacter pylori infection.