Case reports in gastrointestinal medicine · 2026
Metastatic Squamous Cell Carcinoma of the Cervix Presenting With Haematemesis and Duodenal Obstruction: A Case Report and Literature Review.
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Moodley D L, Van Wyk A C, Sungay M Y, Abdelsalem A A, Gabriel M S
Аннотация
BACKGROUND: Metastatic spread of cervical squamous cell carcinoma (SCC) to the duodenum is exceedingly rare, with fewer than 25 cases reported in the literature. Such metastases can present with gastrointestinal symptoms, including upper gastrointestinal bleeding or gastric outlet obstruction (GOO).
CASE PRESENTATION: We report the case of a 58-year-old female with a history of Stage IIB cervical cancer in remission, who presented with haematemesis. Initially, this was ascribed to peptic ulcer disease but was later diagnosed as GOO due to a duodenal mass. Histology confirmed metastatic p16-positive SCC, in keeping with metastatic cervical cancer. The patient's malignant GOO was palliated successfully with the placement of a self-expanding metal stent (SEMS). She died 1 month after discharge.
CONCLUSION: This case highlights an uncommon metastatic pattern of cervical cancer, as well as the diagnostic challenge it can represent. In patients with prior malignancy, a high index of suspicion should be maintained when they present with GOO, regardless of the time interval. It also demonstrates the role of enteral stenting as an effective palliative approach in malignant GOO.
CASE PRESENTATION: We report the case of a 58-year-old female with a history of Stage IIB cervical cancer in remission, who presented with haematemesis. Initially, this was ascribed to peptic ulcer disease but was later diagnosed as GOO due to a duodenal mass. Histology confirmed metastatic p16-positive SCC, in keeping with metastatic cervical cancer. The patient's malignant GOO was palliated successfully with the placement of a self-expanding metal stent (SEMS). She died 1 month after discharge.
CONCLUSION: This case highlights an uncommon metastatic pattern of cervical cancer, as well as the diagnostic challenge it can represent. In patients with prior malignancy, a high index of suspicion should be maintained when they present with GOO, regardless of the time interval. It also demonstrates the role of enteral stenting as an effective palliative approach in malignant GOO.