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Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025

Optimising care for chronic rhinosinusitis with nasal polyps and asthma in multimorbid patients: a multidisciplinary Delphi consensus.

СтатьяConsensus StatementНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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De Corso Eugenio, Vaghi Adriano, Corbò Marco, Pipolo Carlotta, Vultaggio Alessandra, Matucci Andrea, Cantone Elena, Senna Gianenrico, Caminati Marco, Canevari Frank Rikki, Lombardi Carlo, Detoraki Aikaterini, Canonica Giorgio Walter, Schroeder Jan Walter, D'Amato Maria, Crivellaro Maria Angiola, Gelardi Matteo, Salzano Francesco Antonio, Mattavelli Davide, Rampinelli Vittorio, Macchi Alberto, Pasquini Ernesto, Casale Manuele, Gallo Stefania, Pelaia Girolamo, Crimi Claudia, Carpagnano Giovanna Elisiana, Heffler Enrico, Nettis Eustachio, Bilò Maria Beatrice, Seccia Veronica, Ottaviano Giancarlo, Micheletto Claudio, Del Giacco Stefano, Caruso Cristiano, Bagnasco Diego, Bonini Matteo, Menzella Francesco, Passali Giulio Cesare, Maggiore Giandomenico, Di Marco Fabiano, Passali Francesco Maria, Di Michele Loreta, Ricci Giampietro, Galli Jacopo, Pagella Fabio

Аннотация

OBJECTIVE: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma often coexist and share common underlying pathophysiological mechanisms. This study addresses challenges in the diagnosis and treatment of multimorbid patients with CRSwNP and asthma providing new insights for their management.

METHODS: Using a modified Delphi method, a scientific board of 40 Italian clinicians (pulmonologists, allergists/clinical immunologists, and ear, nose, and throat specialists) developed consensus statements regarding the multimorbid patient with severe CRSwNP and asthma and including the disease burden, assessment, treatment and multidisciplinary management of multimorbid patients.

RESULTS: All statements reached consensus. Experts acknowledged the substantial disease burden, the key pathophysiological role of type 2 inflammation in multimorbid patients and the need for multidisciplinary care. The use of biologics represents a highly effective therapeutic opportunity for patients with comorbidities, optimising overall outcomes. Integrated care pathways and regular multidisciplinary re-assessment were deemed essential for treatment decisions and improved care in multimorbid patients.

CONCLUSIONS: This consensus highlights the value of a multidisciplinary approach for multimorbid CRSwNP and asthma patients, advocating for endotype-driven therapies and standardised pathways in clinical practice.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты