Florid polyclonal lymphoid follicular hyperplasia presenting as leopard spot retinopathy.

PURPOSE: To describe a case of leopard spot retinopathy associated with a systemic polyclonal lymphoproliferative disorder. Other described causes of this clinical finding are reviewed.

METHODS

Case report. A previously healthy 50-year-old white male presented with decreased vision. Examination showed leopard spot retinopathy. He underwent ophthalmic and body imaging, laboratory workup, and biopsy of a lymph node and lacrimal gland.

RESULTS

The workup revealed a systemic polyclonal lymphoproliferative disorder which involved the orbit, lymph nodes, pancreas, kidney, and choroid.

CONCLUSION

Leopard spot retinopathy is a clinical description associated with multiple etiologies. Choroidal infiltration related to a systemic polyclonal lymphoproliferative disorder is one cause.