Spontaneous Carcinoogenesis: Regulation of Adhesion Disorders and Cancer Prevention.

Using high-cancer CBA mice we showed that regulation of the expression of β2 leukocyte integrins LFA-1 and Mac-1 on peripheral blood cells, serum levels of IL-6 and IL-10, and number of dopaminergic neurons in combination with CD8+ lymphocyte infiltration of the tumor and destruction of tumor nodes after preventive administration of a multiphytoadaptogen during the early ontogeny substantially affects the incidence and size of spontaneous hepatocarcinomas and increases the duration and quality of life.