American journal of human biology : the official journal of the Human Biology Council · 2025
Association Between Self-Reported Lactose Intolerance, Additional Environmental Factors, and Bone Mineral Density in Young Adults.
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Falbová Darina, Švábová Petra, Beňuš Radoslav, Hozáková Alexandra, Sulis Simona, Vorobeľová Lenka
Аннотация
OBJECTIVES: This study examines the relationship between self-reported lactose intolerance (LI), environmental factors, and their effects on bone mineral density (BMD) in young adults from Slovakia.
METHODS: We assessed 985 adults aged 18-30 years, with an average age of 21.61 ± 2.32 years, who were enrolled in this pilot cross-sectional study during the period 2019-2023. Individual environmental factors (smoking status, alcohol consumption, physical activity, milk and milk product intake, and calcium intake) and self-reported LI were assessed using a detailed questionnaire. BMD was analyzed using the QUS device (Sunlight MiniOmni), and total weight was measured with the InBody 770 bioimpedance analyzer.
RESULTS: Linear regression analysis showed the independent influence of age, total weight, and the presence of LI on the speed of sound in meters per second (SOS; m/s) and Z-score parameters in women (p < 0.05), whereas in men, age and smoking status were significant predictors of SOS (p < 0.05), and age and LI status significantly influenced the Z-score (p < 0.05).
CONCLUSIONS: In the present study of young Slovak adults, the presence of self-reported LI and smoking had a negative effect on BMD, resulting in lower BMD in the radius.
METHODS: We assessed 985 adults aged 18-30 years, with an average age of 21.61 ± 2.32 years, who were enrolled in this pilot cross-sectional study during the period 2019-2023. Individual environmental factors (smoking status, alcohol consumption, physical activity, milk and milk product intake, and calcium intake) and self-reported LI were assessed using a detailed questionnaire. BMD was analyzed using the QUS device (Sunlight MiniOmni), and total weight was measured with the InBody 770 bioimpedance analyzer.
RESULTS: Linear regression analysis showed the independent influence of age, total weight, and the presence of LI on the speed of sound in meters per second (SOS; m/s) and Z-score parameters in women (p < 0.05), whereas in men, age and smoking status were significant predictors of SOS (p < 0.05), and age and LI status significantly influenced the Z-score (p < 0.05).
CONCLUSIONS: In the present study of young Slovak adults, the presence of self-reported LI and smoking had a negative effect on BMD, resulting in lower BMD in the radius.