Human herpesvirus type 4 combined with Brucella abortus meningitis case report.

OBJECTIVE

To observe and analyse the clinical characteristics, diagnosis and treatment of Human herpesvirus type 4 combined with Brucella abortus meningitis, in order to improve clinicians' understanding of this disease.

METHODS

The clinical data of a patient withHuman herpesvirus type 4 combined with Brucella abortus meningitis diagnosed on 8 January 2024 in Baotou People's Hospital were analysed. Results The case was a middle-aged female patient with the main symptoms of dizziness and numbness and weakness of the limbs. The pathogenic microorganisms were detected as macrogenomic and copy number anomalies by double-homology: Human herpesvirus type 4 was detected as sequence number 13, and the serum Brucella abortus tiger-red plate agglutination test was positive.

RESULTS

Brucella tube agglutination test: 1:400 ++. Symptoms improved significantly after treatment with doxycycline + rifampicin + cotrimoxazole tablets and prednisone acetate tablets.

CONCLUSION

Human herpesvirus type 4 (EBV) combined with Brucella abortus meningitis is a rare infectious encephalitis with a poor prognosis and high recurrence rate. A step therapy strategy of antibiotics combined with glucocorticoids is currently recommended to control acute phase symptoms and reduce the risk of recurrence.