Internal medicine (Tokyo, Japan) · 2025
Decompensated Cirrhosis with Hepatopulmonary Syndrome in a Patient with Interrupted Treatment for Hypopituitarism.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Tadokoro Tomoko, Tani Joji, Sato Yudai, Yano Rie, Takuma Kei, Nakahara Mai, Oura Kyoko, Fujita Koji, Ono Masafumi, Tobiume Atsushi, Sato Seisuke, Inoue Takuya, Morishita Asahiro, Kobara Hideki
Аннотация
A 32-year-old man presented with cirrhosis. At 8 years of age, he underwent resection of a craniopharyngioma, which resulted in panhypopituitarism. He underwent self-interrupted hormone replacement therapy at 20 years of age. Computed tomography revealed severe fatty liver and cirrhosis. An endocrinological evaluation revealed panhypopituitarism. Further assessment revealed a diagnosis of hepatopulmonary syndrome. Home oxygen therapy and hormone replacement therapy were initiated. Despite these efforts, poorly controlled hypothalamic obesity led to liver failure, and the patient is currently awaiting liver transplantation. Liver cirrhosis associated with long-term panhypopituitarism may have a poor prognosis even with hormone replacement therapy.