Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2008
An exploratory analysis of neurocognition in methamphetamine-induced psychotic disorder and paranoid schizophrenia.
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Jacobs Elizabeth, Fujii Daryl, Schiffman Jason, Bello Iruma
Аннотация
OBJECTIVE: This exploratory study compared the neurocognitive performances of individuals with methamphetamine-induced psychotic disorder (MA psychosis) and paranoid schizophrenia.
BACKGROUND: MA psychosis presents very similarly to paranoid schizophrenia and the relationship between the 2 disorders is not well-understood. Neurocognitive functioning is one potential factor for comparison, as deficits are documented in both schizophrenia and methamphetamine dependence.
METHOD: Participants were selected through chart review. Neurocognitive test scores for participants with paranoid schizophrenia (n=20) and MA psychosis (n=19) were obtained from hospital records and compared.
RESULTS: Results of multivariate analysis of variance found no significant differences between the groups in any neurocognitive domain.
CONCLUSIONS: These preliminary findings suggest that similarities between the disorders may extend to neurocognition. Low power and sampling limitations may contribute to the null findings.
BACKGROUND: MA psychosis presents very similarly to paranoid schizophrenia and the relationship between the 2 disorders is not well-understood. Neurocognitive functioning is one potential factor for comparison, as deficits are documented in both schizophrenia and methamphetamine dependence.
METHOD: Participants were selected through chart review. Neurocognitive test scores for participants with paranoid schizophrenia (n=20) and MA psychosis (n=19) were obtained from hospital records and compared.
RESULTS: Results of multivariate analysis of variance found no significant differences between the groups in any neurocognitive domain.
CONCLUSIONS: These preliminary findings suggest that similarities between the disorders may extend to neurocognition. Low power and sampling limitations may contribute to the null findings.