Veterinary anaesthesia and analgesia · 2026
Comparison of three anesthetic protocols in 146 olive baboons (Papio anubis) in a mass capture event for physical examination and surgical sterilization.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chang Hong-Yi, Yang Nian-Yao
Аннотация
OBJECTIVE: To compare three anesthetic protocols used in olive baboons (Papio anubis).
STUDY DESIGN: Retrospective, observational, clinical study.
ANIMALS: A group of 146 adult olive baboons housed at a single safari facility.
METHODS: Anesthesia records from a mass capture were reviewed. Animals were immobilized using one of three protocols administered intramuscularly: dexmedetomidine 0.02 mg kg-1 and tiletamine-zolazepam 3 mg kg-1 (DTZ), xylazine 0.5 mg kg-1 and tiletamine-zolazepam 3 mg kg-1 (XTZ), or xylazine 0.5 mg kg-1 and midazolam 0.1 mg kg-1 and ketamine 3 mg kg-1 (XMK). Data collected included demographic information, anesthetic induction and procedure times, need for supplemental drugs during induction or maintenance, and adverse events. Descriptive statistics and independent t-tests were used to compare between groups, with significance set at p < 0.05.
RESULTS: All animals were successfully immobilized and recovered from immobilization with no adverse events observed. DTZ produced the shortest induction times (297 ± 108 seconds), compared with XTZ (356 ± 123 seconds) and XMK (449 ± 83 seconds). Supplemental anesthetics were administered during induction in 9.4% (6/64, DTZ), 11.0% (8/73, XTZ), and 22.2% (2/9, XMK) of cases. One animal in the XTZ group developed bradycardia (heart rate < 60 beats minute-1) and hypotension (oscillometric mean arterial blood pressure < 60 mmHg) during anesthesia that was successfully treated with anticholinergic agents. Animals breathed spontaneously throughout immobilizations.
CONCLUSIONS AND CLINICAL RELEVANCE: DTZ achieved rapid induction with a lower need for supplemental anesthesia than both XTZ and XMK. A randomized, blinded trial is required to properly compare drug protocols.
STUDY DESIGN: Retrospective, observational, clinical study.
ANIMALS: A group of 146 adult olive baboons housed at a single safari facility.
METHODS: Anesthesia records from a mass capture were reviewed. Animals were immobilized using one of three protocols administered intramuscularly: dexmedetomidine 0.02 mg kg-1 and tiletamine-zolazepam 3 mg kg-1 (DTZ), xylazine 0.5 mg kg-1 and tiletamine-zolazepam 3 mg kg-1 (XTZ), or xylazine 0.5 mg kg-1 and midazolam 0.1 mg kg-1 and ketamine 3 mg kg-1 (XMK). Data collected included demographic information, anesthetic induction and procedure times, need for supplemental drugs during induction or maintenance, and adverse events. Descriptive statistics and independent t-tests were used to compare between groups, with significance set at p < 0.05.
RESULTS: All animals were successfully immobilized and recovered from immobilization with no adverse events observed. DTZ produced the shortest induction times (297 ± 108 seconds), compared with XTZ (356 ± 123 seconds) and XMK (449 ± 83 seconds). Supplemental anesthetics were administered during induction in 9.4% (6/64, DTZ), 11.0% (8/73, XTZ), and 22.2% (2/9, XMK) of cases. One animal in the XTZ group developed bradycardia (heart rate < 60 beats minute-1) and hypotension (oscillometric mean arterial blood pressure < 60 mmHg) during anesthesia that was successfully treated with anticholinergic agents. Animals breathed spontaneously throughout immobilizations.
CONCLUSIONS AND CLINICAL RELEVANCE: DTZ achieved rapid induction with a lower need for supplemental anesthesia than both XTZ and XMK. A randomized, blinded trial is required to properly compare drug protocols.