Arquivos brasileiros de oftalmologia · 2025
Perioperative subconjunctival steroid injection in dropless cataract surgery: a systematic review and meta-analysis.
Систематический обзорСтатьяМетаанализНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Cyrino Laura Goldfarb, Amaral Dillan, Fujimura Júnior Alexandre Yamada, Parekh Bela J, Bastos Marcela Marino de Azeredo, Gaio Giovana de Souza, Arteche Maria Antônia Torres, Nascimento Amanda Souza do, Ribeiro Vitor Expedito Alves, Guedes Jaime, Hollaender Marianna Almeida
Аннотация
The advantages and disadvantages of using perioperative subconjunctival steroid injections in dropless cataract surgery continue to be debated. A systematic review of PubMed, EMBASE, and the Cochrane Central database identified five studies-two randomized controlled trials and three non-randomized studies-encompassing 70,751 eyes. Among these, 12,319 eyes (17.4%) received subconjunctival steroid injections, while 58,432 eyes (82.6%) were managed with topical steroids. The Cochrane Collaboration's RoB 2 tool was applied for bias assessments in randomized controlled trials, and heterogeneity was assessed using the I² statistics. No statistically significant differences were found between the two groups regarding macular edema (p=0.249), visual acuity (p=0.73), or laser flare count (p=0.45). Both subconjunctival injections and topical steroids demonstrated comparable efficacy and safety in controlling postoperative inflammation after cataract surgery. Additional research is warranted to validate these conclusions.