Oncological Feasibility of Limited Neck Dissection in cN0 Supraglottic Laryngeal Cancer.
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Bassani Sara, Papi Giacomo, Marani Filippo, Nocini Riccardo, Campagnari Valentina, Marchi Filippo, Lionello Marco, Varago Chiara, Paderno Alberto, Crosetti Erika, Mattioli Francesco, Serafini Edoardo, Fermi Matteo, Rosti Alessandro, Petruzzi Gerardo, Campo Flaminia, Bellini Elisa, Marcuzzo Alberto Vito, Mineo Chiara Angela, Mercante Giuseppe, De Virgilio Armando, Giordano Leone, Galli Andrea, Mannelli Giuditta, Mazzetti Luca, Paludetti Gaetano, Rossi Giorgia, Zeleník Karol, Ramos Daniel Marin, Dedivitis Rogèrio Aparecido, Succo Giovanni, Tirelli Giancarlo, Bussi Mario, Pellini Raul, Galli Jacopo, Spriano Giuseppe, Monzani Daniele, Peretti Giorgio, Bertolin Andy, Piazza Cesare, Marchioni Daniele, Presutti Livio, Molteni Gabriele
Аннотация
METHODS: This study is a retrospective, multicenter examination of the potential feasibility of limited neck dissection (LND), including only levels IIa and III in cN0 supraglottic SCC patients. It analyzed occult metastasis rates and explored relapse occurrences alongside potential predictors of lymph node metastasis.
RESULTS: Among 425 patients, predominantly male (85.6%) with a mean age of 63 years, the occult metastasis rate was 28.9%, and 13.7% experienced relapses during a mean follow-up of 52 months. Advanced clinical stage, higher grading, and other risk factors emerged as predictors of occult lymph node metastasis at level IIb.
CONCLUSIONS: The study supports LND potential feasibility for cN0 supraglottic SCC, suggesting level IIb dissection can be omitted in specific early-stage cases to reduce morbidity without affecting outcomes.