Sleep duration inversely correlates with glucolipid metabolism in patients with new-onset type 2 diabetes mellitus.

OBJECTIVE

To study the correlation between sleep duration and glucolipid metabolism in patients with new-onset type 2 diabetes mellitus (NOT2DM).

METHODS

The participants were 168 NOT2DM patients. Glucolipid metabolism indices were compared among the short (n=59), middle (n=56), and long sleep groups (n=53), including fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), total cholesterol (TC), and triglyceride (TG). The correlation of sleep duration with glucolipid metabolism, glycemic control, and body fat distribution (abdominal total fat area [TFA] and visceral fat area [VFA]) was assessed. Finally, the contributors to poor glycemic control were explored.

RESULTS

Glucolipid metabolism indices tended to decrease with increasing sleep duration in NOT2DM patients, suggesting a significant negative correlation between sleep duration and glucolipid metabolism. The sleep duration of the good glycemic control group was significantly longer. A significant positive correlation was identified between sleep duration and good glycemic control, while an inverse association was determined between sleep duration and TFA. Body mass index (BMI), sleep duration, FBG, TG, and TFA were all independent contributors to poor glycemic control.

CONCLUSIONS

Sleep duration in NOT2DM patients was inversely related to glucolipid metabolism and TFA and positively correlated with good glycemic control. High BMI, FBG, TG, and TFA, as well as short sleep duration, may increase the risk of poor glycemic control.