[Pancreatogenic Diabetes: The Exocrine-Endocrine Axis].

UNLABELLED: Pancreatogenic diabetes is a specific form of diabetes secondary to exocrine pancreatic disease. It is often misclassified or confused with other types of diabetes. It is not a single clinical entity but occurs in association with various exocrine pancreatic disorders, through diffe-rent mechanisms of hyperglycemia. This condition is associated with an increased risk of hypoglycemia, making close clinical monitoring essential.

AIM: To review the physiological and pathophysiological aspects of the exocrine-endocrine interplay of the pancreas, as well as the clinical features of this specific type of diabetes, in order to support accurate diagnosis, treatment, and follow-up.

METHODOLOGY: Narrative review.

RESULTS

A multidisciplinary overview of pancreatogenic diabetes is presented, covering its definition, pathogenesis, epidemiology, and management, integrating both endocrine and exocrine pancreatic perspectives.

CONCLUSIONS

The management of pancreatogenic diabetes should be multidisciplinary and individualized, with a focus on preventing and treating malnutrition, and combining insulin therapy with pancreatic enzyme replacement therapy.