Treatment of Gastric Cancer: Laparoscopic Pylorus-Preserving Gastrectomy or Laparoscopic Distal Gastrectomy? A Systematic Review and Meta-Analysis.

BACKGROUND AND

OBJECTIVES

The aim of this study is to compare the efficacy of the laparoscopic pylorus-preserving gastrectomy (LPPG) and laparoscopic distal gastrectomy (LDG) for gastric cancer (GC) on postoperative complications and nutritional status.

METHODS

We conducted a literature search of PubMed, EMBASE, Scopus, and Cochrane Library databases before April 20th, 2025.

RESULTS

We found that the rate of delayed gastric emptying and gastric stasis after LPPG was higher than that after LDG, while there was no significant difference in the incidence of pulmonary diseases, anastomotic leakage, pulmonary fistula, or other complications. The prevention of dumping syndrome and the improvement in nutritional status seemed to be better in LPPG.

CONCLUSIONS

No more valuable benefits of LDG in reducing complications was found.