Early Cardiac Intervention Decreases the Mortality Risk Linked With Marfan Syndrome.

Early cardiovascular intervention, such as valve repairs, can extend the life expectancy of patients with Marfan syndrome (MFS) by improving blood flow, preventing regurgitation, and optimizing preload and afterload. These improvements enhance ventricular function, ultimately reducing both cardiac and respiratory symptoms. More commonly, patients with MFS can develop aortic root dilation and mitral valve prolapse as a result of a diseased valve. The combination of cardiac repairs and proper medication adherence can decrease the mortality risk linked with MFS. More specifically, aortic and mitral valve repairs can restore the functions of the aorta, left ventricle, and left atrium, respectively, and reduce further complications leading to aortic dissection and heart failure.