Traditional Chinese medicine alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection: A complementary perspective.

Liu et al recently published research suggesting that multistrain probiotics significantly relieved bismuth quadruple therapy (BQT)-associated gastrointestinal symptoms without affecting eradication success. They conducted a rigorous randomized, double-blind, placebo-controlled trial, demonstrating that a 4-week regimen of a multistrain probiotic supplement significantly reduced symptoms such as reflux, dyspepsia, and diarrhea. The reduction in side effects and enhanced patient comfort highlight the clinical utility of probiotics as a safe and well-tolerated adjunct to BQT. Our contribution was about to involve the traditional Chinese medicine treating Helicobacter pylori-related chronic gastritis. They can have similar functions in regulating gut microbiota. Future research should build on this foundation to refine probiotic formulations, explore their long-term effects, and clarify their role in achieving higher eradication rates.