Diabetes mellitus and Degos disease.

We present the case of a 75-year-old man who was diagnosed with Degos disease (DD) in the context of type 2 diabetes mellitus. The cutaneous lesions of DD were located at the trunk as well as in the proximal parts of the arms. He presented with positive laboratory test for lupic anticoagulant, but other rheumatologic parameters of interest were within normal limits. The skin biopsy corroborated the diagnosis of DD, and also showed morphologic features traditionally associated to hyaline diabetic microangiopathy. Since the latter has recently been atributted to C5b-9 deposit in the vessel wall, we discuss if both conditions are pathogentically connected or just coincidental (Fig. 3, Ref. 32). Full Text (Free, PDF) www.bmj.sk.