Membrane-associated immunoglobulin determinants on bone marrow and blood lymphocytes in the pediatric age group and on fetal tissues.
Lymphocytes from bone marrow and blood of infants and children and from various tissues of seven fetuses between 13 and 25 weeks of gestational age were studied by immunofluorescence for the presence of membrane-associated immunoglobulins. Cells with mu and delta determinants prevailed, and these immunoglobulins were usually present on the same cell. The bone marrow specimens of all age groups contained more mu-positive cells without delta determinants than did the samples from the peripheral blood. Such mu(+)delta(-) cells were also found in tissues of young fetuses. These cells were postulat
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