Signal mining of botulinum toxin type A adverse events based on FAERS database and its implications for the treatment of cerebral palsy.
OBJECTIVE: Based on the US Food and Drug Administration Adverse Event Reporting System (FAERS), signal mining of adverse drug events (AEs) caused by Botulinum Toxin Type A (BoNTA) was performed to explore its safety implications for the treatment of cerebral palsy (CP). METHODS: The OpenVigil 2.1 platform was used to extract AE reports on BoNTA from the FAERS database, covering the period from the fourth quarter of 2003 to the second quarter of 2024. Safety data were analyzed using the Reporting Odds Ratio (ROR) and Proportional Reporting Ratio (PRR), with BoNTA designated as the primary susp
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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